Description

5-Bromo-2-Chloro-4-Isopropoxypyrimidine is a high-purity halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its molecular structure makes it an indispensable intermediate for the development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key synthon in the synthesis of novel nucleoside analogs and other bioactive molecules targeting viral and oncological diseases.
• Agrochemical Research: Used as a precursor in developing new generation herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and liquid crystals.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for methodological development and discovery chemistry.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Isopropoxypyrimidine
CAS No.	1289215-25-3
Molecular Formula	C7H8BrClN2O
Molecular Weight	251.51 g/mol
Synonyms	4-Isopropoxy-5-bromo-2-chloropyrimidine; 2-Chloro-5-bromo-4-isopropoxypyrimidine; 5-Bromo-2-chloro-4-(propan-2-yloxy)pyrimidine; 5-Bromo-2-chloro-4-(1-methylethoxy)pyrimidine; Pyrimidine, 5-bromo-2-chloro-4-(1-methylethoxy)-; 1289215-25-3; BCP Intermediate
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-4-Isopropoxypyrimidine is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, NMR, and MS is supplied with each shipment to guarantee reproducible results and supply chain integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.