Description

2-Trifluoromethyl-4-Methylthiobenzaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of the electron-withdrawing trifluoromethyl group and the versatile methylthio moiety, which enables precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials requiring specific electronic characteristics.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological mechanisms and interactions.

Basic Information

Product Name	2-Trifluoromethyl-4-Methylthiobenzaldehyde
CAS No.	1289164-55-1
Molecular Formula	C9H7F3OS
Molecular Weight	220.21 g/mol
Synonyms	4-(Methylthio)-2-(trifluoromethyl)benzaldehyde; 2-(Trifluoromethyl)-4-(methylsulfanyl)benzaldehyde; 4-Methylsulfanyl-2-trifluoromethylbenzaldehyde; 2-Trifluoromethyl-4-methylmercaptobenzaldehyde; α,α,α-Trifluoro-4-(methylthio)-o-tolualdehyde; Benzaldehyde, 4-(methylthio)-2-(trifluoromethyl)-; 1289164-55-1
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-4-Methylthiobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.