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5-Bromo-2-(2-Methoxyethoxy)Pyrimidine CAS NO 1289131-96-9
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CAS No.:1289131-96-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Bromo-2-(2-methoxyethoxy)pyrimidine is a high-purity, functionalized pyrimidine derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, offering both a bromine atom for cross-coupling reactions and an alkoxyether side chain for solubility and molecular tuning. This compound is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.
Application
- Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
- Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
- Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
- Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
- Chemical Biology: Employed as a probe or linker in bioconjugation and the development of chemical tools.
- Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific molecule construction.
Basic Information
| Product Name | 5-Bromo-2-(2-methoxyethoxy)pyrimidine |
| CAS No. | 1289131-96-9 |
| Molecular Formula | C7H9BrN2O2 |
| Molecular Weight | 233.06 g/mol |
| Synonyms | 2-(2-Methoxyethoxy)-5-bromopyrimidine; 5-Bromo-2-(2-methoxyethoxy)pyrimidine; Pyrimidine, 5-bromo-2-(2-methoxyethoxy)-; 1289131-96-9; 5-Bromo-2-(2-methoxy-ethoxy)-pyrimidine |
| EINECS | Contact for details |
Quality Control
Our 5-Bromo-2-(2-methoxyethoxy)pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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