Description

3-Bromo-2-(Trifluoromethyl)Benzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl and bromo substituents for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often confers improved activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to build complex biaryl systems.
• Fine Chemical Production: A building block for dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	3-Bromo-2-(Trifluoromethyl)Benzaldehyde
CAS No.	1289057-68-6
Molecular Formula	C8H4BrF3O
Molecular Weight	253.02 g/mol
Synonyms	3-Bromo-2-(trifluoromethyl)benzaldehyde; 2-(Trifluoromethyl)-3-bromobenzaldehyde; 3-Bromo-α,α,α-trifluoro-o-tolualdehyde; Benzaldehyde, 3-bromo-2-(trifluoromethyl)-; o-(Trifluoromethyl)-m-bromobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.