Description

4,6-Dichloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Pyrimidine is a high-value heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, where the chloropyrimidine moiety and the pyrazole ring offer distinct handles for selective derivatization, enabling the construction of complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used as a core scaffold for developing new generations of herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Biology Probe Development: Serves as a versatile starting point for creating tool compounds to study biological pathways and protein functions.
• Material Science: Potential building block for the synthesis of specialized polymers, ligands for catalysis, or organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise heterocyclic core.

Basic Information

Product Name	4,6-Dichloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Pyrimidine
CAS No.	1289010-13-4
Molecular Formula	C8H6Cl2N4
Molecular Weight	229.07 g/mol
Synonyms	2-(3-Methyl-1H-pyrazol-1-yl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-(3-methylpyrazol-1-yl)pyrimidine; 1-(4,6-Dichloropyrimidin-2-yl)-3-methyl-1H-pyrazole; 4,6-Dichloro-2-(3-methyl-1H-pyrazol-1-yl)pyrimidine; 1289010-13-4
EINECS	Contact for details

Quality Control

Our production of 4,6-Dichloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Pyrimidine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A detailed Certificate of Analysis (COA) providing purity, identity confirmation, and impurity profile is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.