Description

5-Bromo-2-Chloro-4-Ethoxypyrimidine is a high-purity halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its versatile reactivity, enabling the precise construction of complex molecular architectures for research and development. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution for introducing the pyrimidine core.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic institutions and CROs/CDMOs.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Ethoxypyrimidine
CAS No.	1289005-72-6
Molecular Formula	C6H6BrClN2O
Molecular Weight	237.48 g/mol
Synonyms	4-Ethoxy-5-bromo-2-chloropyrimidine; 2-Chloro-5-bromo-4-ethoxypyrimidine; 5-Bromo-2-chloro-4-ethoxy-pyrimidine; Pyrimidine, 5-bromo-2-chloro-4-ethoxy-; 1289005-72-6; 5-Br-2-Cl-4-EtO-Pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-Ethoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.