Description

3-Fluoro-2-(Neopentyloxy)Aniline is a specialized fluorinated aniline derivative featuring a sterically hindered neopentyloxy substituent. This unique molecular architecture makes it a high-value intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D and agrochemical development teams for constructing complex molecules requiring specific steric and electronic properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to create advanced herbicides and fungicides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated aromatic components in electronic display technologies.
• Polymer Modification: Imparts specific functionalities into polymer backbones for specialty high-performance resins.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) due to its aniline functionality.
• Dye & Pigment Intermediate: Used in the production of specialized fluorinated colorants.

Basic Information

Product Name	3-Fluoro-2-(Neopentyloxy)Aniline
CAS No.	1286274-36-9
Molecular Formula	C₁₁H₁₆FNO
Molecular Weight	197.25 g/mol
Synonyms	2-(Neopentyloxy)-3-fluoroaniline; 3-Fluoro-2-(2,2-dimethylpropoxy)aniline; 1-Fluoro-2-amino-6-(neopentyloxy)benzene; Benzenamine, 3-fluoro-2-(2,2-dimethylpropoxy)-; 3-Fluoro-2-neopentyloxyaniline; 3-FA-NPOA; FNOA Intermediate
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Neopentyloxy)Aniline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation by NMR, IR, and GC-MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.