Description

3-Fluoro-4-(Neopentyloxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique neopentyl-protected aniline structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its fluorine substituent and sterically hindered alkoxy group are key for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor for functional dyes and electronic chemicals used in display technologies.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex aromatic amines via further functionalization.
• Chemical Research & Development: Essential for method development and scale-up studies in process chemistry.

Basic Information

Product Name	3-Fluoro-4-(Neopentyloxy)Aniline
CAS No.	1286264-83-2
Molecular Formula	C11H16FNO
Molecular Weight	197.25 g/mol
Synonyms	4-(Neopentyloxy)-3-fluoroaniline; 3-Fluoro-4-neopentyloxyaniline; Benzenamine, 3-fluoro-4-(2,2-dimethylpropoxy)-; 3-Fluoro-4-(2,2-dimethylpropoxy)aniline; 3-Fluoro-4-(tert-pentyloxy)aniline; 3-FA-NPOA; F-NP-Aniline
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-(Neopentyloxy)Aniline is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.