Description

2-(Pyrimidin-2-Ylamino)-1,3-Thiazole-4-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes and labeled compounds for studying biological mechanisms and target engagement.
• Material Science: Acts as a building block for advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or functional polymers.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry and medicinal chemistry programs.
• Custom Synthesis & Scale-Up: Provided for custom manufacturing projects, from milligram-scale feasibility studies to multi-kilogram process development.

Basic Information

Product Name	2-(Pyrimidin-2-Ylamino)-1,3-Thiazole-4-Carboxylic Acid
CAS No.	1283109-30-7
Molecular Formula	C8H6N4O2S
Molecular Weight	222.22 g/mol
Synonyms	2-[(Pyrimidin-2-yl)amino]-1,3-thiazole-4-carboxylic acid; 2-(Pyrimidin-2-ylamino)thiazole-4-carboxylic acid; 4-Carboxy-2-(pyrimidin-2-ylamino)thiazole; Thiazole-4-carboxylic acid, 2-(2-pyrimidinylamino)-; 1283109-30-7; 2-Pyrimidin-2-ylaminothiazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(Pyrimidin-2-Ylamino)-1,3-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support development and commercial projects with reliable, traceable, and high-quality material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.