Description

{2-[(Pyrimidin-2-Ylcarbonyl)Amino]-1,3-Thiazol-4-Yl}Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and anti-infectives. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and production of potential kinase inhibitors used in cancer therapy.
• Antimicrobial Agent Research: Used in the discovery and development of new antibacterial or antifungal compounds due to its thiazole-pyrimidine structure.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-complexity intermediates.
• Academic Research: Used in university and institutional labs for medicinal chemistry programs and heterocyclic compound research.

Basic Information

Product Name	{2-[(Pyrimidin-2-Ylcarbonyl)Amino]-1,3-Thiazol-4-Yl}Acetic Acid
CAS No.	1283109-10-3
Molecular Formula	C10H7N5O3S
Molecular Weight	277.26 g/mol
Synonyms	2-({[(Pyrimidin-2-yl)carbonyl]amino}-1,3-thiazol-4-yl)acetic acid; 2-[[(Pyrimidine-2-carbonyl)amino]-1,3-thiazol-4-yl]acetic acid; 4-Carboxymethyl-2-[(pyrimidine-2-carboxamido)]thiazole; (2-((Pyrimidine-2-carboxamido)thiazol-4-yl)acetic acid; CAS 1283109-10-3
EINECS	Contact for details

Quality Control

Our {2-[(Pyrimidin-2-Ylcarbonyl)Amino]-1,3-Thiazol-4-Yl}Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.