Description

α-Ketoglutaric Acid Disodium Salt Dihydrate is a high-purity, water-soluble salt form of the key metabolic intermediate α-ketoglutarate. This compound matters for its critical role in cellular energy production, amino acid synthesis, and as a precursor in various biochemical pathways. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and cell culture media industries, where it serves as a vital component in fermentation processes, diagnostic reagents, and advanced nutritional supplements.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and as a key component in cell culture media for biopharmaceutical production.
• Nutraceuticals & Dietary Supplements: Incorporated into formulations targeting energy metabolism, athletic performance, and anti-aging due to its role in the Krebs cycle.
• Biochemical Research: Serves as a standard, substrate, or buffer component in enzymatic assays and metabolic studies.
• Diagnostic Reagents: Utilized in clinical diagnostic kits for the measurement of transaminase enzymes (AST, ALT) in blood serum.
• Microbial Fermentation: Acts as a crucial nutrient and metabolic precursor in fermentation processes for the production of amino acids like L-ornithine and L-arginine.
• Cosmeceuticals: Explored in skincare formulations for its potential role in collagen synthesis and cellular energy support.

Basic Information

Product Name	α-Ketoglutaric Acid Disodium Salt Dihydrate
CAS No.	1282616-74-3
Molecular Formula	C5H6Na2O5 · 2H2O
Molecular Weight	226.08 g/mol (anhydrous basis)
Synonyms	2-Oxoglutaric Acid Disodium Salt Dihydrate; AKG Disodium Salt; α-Ketoglutarate Disodium Salt Dihydrate; Sodium 2-Oxopentanedioate Dihydrate; Oxoglutaric Acid Disodium Salt Dihydrate; 2-Oxopentanedioic Acid Disodium Salt Dihydrate; Disodium α-Ketoglutarate Dihydrate
EINECS	Contact for details

Quality Control

Our α-Ketoglutaric Acid Disodium Salt Dihydrate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and production use. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
pH (5% Solution)	6.5 - 8.5
Water (Karl Fischer)	14.0% - 17.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.