Description

3-Bromo-4-Ethoxy-5-Fluoroaniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for precise molecular modifications in the creation of complex target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl and other complex structures.
• Chemical Biology Probes: Used to create tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Product Name	3-Bromo-4-Ethoxy-5-Fluoroaniline
CAS No.	1280786-90-4
Molecular Formula	C8H9BrFNO
Molecular Weight	234.07 g/mol
Synonyms	5-Fluoro-3-bromo-4-ethoxyaniline; 4-Ethoxy-5-fluoro-3-bromoaniline; 3-Bromo-4-ethoxy-5-fluorobenzenamine; Benzenamine, 3-bromo-4-ethoxy-5-fluoro-; 2-Bromo-4-amino-5-fluorophenetole; 1-Amino-2-bromo-4-ethoxy-5-fluorobenzene; 5-Fluoro-4-ethoxy-3-bromoaniline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Ethoxy-5-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards as required for your specific application.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.