Description

tert-Butyl(2-Chloropyrimidin-5-Yl)Methylcarbamate is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile reactive site for further functionalization. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its pyrimidine core structure.
• Chemical Research & Development: Serves as a versatile precursor for creating custom libraries of compounds for high-throughput screening.
• Peptide Mimetics & Conjugates: The carbamate and chloropyrimidine groups allow for selective coupling reactions in bioconjugation and peptide chemistry.
• Material Science: Potential use as a monomer or functional additive in the development of specialty polymers and functional materials.

Basic Information

Product Name	tert-Butyl(2-Chloropyrimidin-5-Yl)Methylcarbamate
CAS No.	1279820-16-4
Molecular Formula	C10H14ClN3O2
Molecular Weight	243.69 g/mol
Synonyms	tert-Butyl N-[(2-chloropyrimidin-5-yl)methyl]carbamate; Carbamic acid, N-[(2-chloro-5-pyrimidinyl)methyl]-, 1,1-dimethylethyl ester; 5-[[(tert-Butoxycarbonyl)amino]methyl]-2-chloropyrimidine; 2-Chloro-5-[(tert-butoxycarbonylamino)methyl]pyrimidine; Boc-2-chloro-5-aminomethylpyrimidine; (2-Chloropyrimidin-5-yl)methyl tert-butylcarbamate; tert-Butyl (2-chloro-5-pyrimidinylmethyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl(2-Chloropyrimidin-5-Yl)Methylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.