Description

5-Chloromethyl-Pyrimidine-2-Carboxylic Acid CAS NO 1279816-04-4 is a high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a reactive chloromethyl group, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and kinase inhibitor applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Ligand & Chelator Synthesis: Building block for creating complex ligands used in catalysis and metal coordination chemistry.
• Material Science: Intermediate for synthesizing functionalized polymers and specialty chemicals.

Basic Information

Product Name	5-Chloromethyl-Pyrimidine-2-Carboxylic Acid
CAS No.	1279816-04-4
Molecular Formula	C7H5ClN2O2
Molecular Weight	184.58 g/mol
Synonyms	2-Pyrimidinecarboxylic acid, 5-(chloromethyl)-; 5-(Chloromethyl)pyrimidine-2-carboxylic acid; 5-Chloromethyl-2-pyrimidinecarboxylic acid; 1279816-04-4; 5-(Chloromethyl)-2-pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloromethyl-Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed specifications, including assay by HPLC, impurity profile, and physical characterization. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.