Description

Fmoc-A-Cyclopentyl-Dl-Glycine CAS NO 1276562-78-7 is a non-natural, Fmoc-protected amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for the development of novel peptide-based pharmaceuticals and research tools, offering structural diversity to modulate biological activity and stability. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers specializing in peptide drug discovery and custom synthesis.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptides, particularly those requiring cyclopentylglycine analogs.
• Peptidomimetic Drug Discovery: Used to incorporate the cyclopentyl moiety into peptide backbones, enhancing metabolic stability, lipophilicity, and receptor binding affinity in drug candidates.
• Combinatorial Chemistry Libraries: Serves as a valuable scaffold for generating diverse libraries of peptide-like compounds for high-throughput screening against biological targets.
• Bioconjugation and Probe Development: Acts as a precursor for creating labeled peptides or peptide-based imaging agents and diagnostic tools.
• Academic and Industrial Research: Essential for fundamental studies in peptide chemistry, structure-activity relationships (SAR), and molecular biology.

Basic Information

Product Name	Fmoc-A-Cyclopentyl-Dl-Glycine
CAS No.	1276562-78-7
Molecular Formula	C₂₃H₂₅NO₄
Molecular Weight	379.45 g/mol
Synonyms	Fmoc-α-Cyclopentyl-DL-glycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-α-cyclopentylglycine; Fmoc-Cpg(DL)-OH; Fmoc-DL-α-Cyclopentylglycine; (RS)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-2-cyclopentylacetic acid; N-Fmoc-α-cyclopentylglycine; Fmoc-α-Cyclopentylglycine, DL-; 2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclopentylacetic acid
EINECS	Contact for details

Quality Control

Our Fmoc-A-Cyclopentyl-Dl-Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify the DL-mixture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.