Description

(R)-2-(Aminomethyl)-3-Methylbutanoic Acid-Hcl CAS NO 1276055-45-8 is a high-purity chiral amino acid derivative, specifically the hydrochloride salt of the (R)-enantiomer. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, where stereochemical purity is paramount for biological activity. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of APIs, especially for neurological and metabolic drugs.
• Peptidomimetics Research: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability and bioavailability.
• Ligand Synthesis: Serves as a precursor for chiral ligands in asymmetric catalysis and metal complex formation.
• Protease Inhibitor Development: A building block for creating inhibitors targeting specific enzymes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific chiral centers into target molecules.

Basic Information

Product Name	(R)-2-(Aminomethyl)-3-Methylbutanoic Acid Hydrochloride
CAS No.	1276055-45-8
Molecular Formula	C7H15NO2 • HCl
Molecular Weight	181.66 g/mol (Free base: 145.20 g/mol)
Synonyms	(R)-2-(Aminomethyl)-3-methylbutanoic acid hydrochloride; (R)-2-(Aminomethyl)-3-methylbutyric acid HCl; (R)-Homo-valine hydrochloride; D-2-(Aminomethyl)-3-methylbutanoic acid hydrochloride; (R)-3-Methyl-2-(aminomethyl)butanoic acid hydrochloride; (2R)-2-(Aminomethyl)-3-methylbutanoic acid hydrochloride; (R)-2-Aminomethyl-3-methylbutyric acid hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-(Aminomethyl)-3-Methylbutanoic Acid-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.