Description

D-β-Homoleucine-Hcl is a high-purity, non-proteinogenic amino acid derivative used in advanced pharmaceutical research and development. This compound is valued for its role as a critical chiral building block in the synthesis of complex peptides and active pharmaceutical ingredients (APIs). It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, stereochemically defined intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide-based therapeutics and APIs.
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis to introduce specific structural modifications.
• Proteomics & Biochemical Studies: Serves as a specialized component in the study of enzyme-substrate interactions and metabolic pathways.
• Ligand & Catalyst Development: Employed in the design and synthesis of chiral ligands for asymmetric catalysis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Academic & Industrial R&D: Fundamental building block for exploratory chemistry in both academic institutions and corporate R&D departments.

Basic Information

Product Name	D-β-Homoleucine-Hcl
CAS No.	1276055-44-7
Molecular Formula	C7H15NO2 • HCl
Molecular Weight	197.66 g/mol (Free base: 145.20 g/mol)
Synonyms	D-β-Homoleucine hydrochloride; (R)-2-Amino-4-methylhexanoic acid hydrochloride; D-2-Amino-4-methylhexanoic acid HCl; (R)-β-Homoleucine HCl; D-β-Homoleucine hydrochloride; D-β-Hle-OH • HCl; (2R)-2-Amino-4-methylhexanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our D-β-Homoleucine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.