Description

1-(4-Methyl-2-Pyrimidinyl)-4-Piperidinecarboxylic Acid Ethyl Ester is a high-purity pharmaceutical intermediate and versatile organic building block. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Synthesis Building Block: Employed in the construction of more complex heterocyclic compounds due to its reactive ester and piperidine-pyrimidine structure.
• API Development: Serves in the developmental pathway for potential new therapeutic agents requiring a functionalized piperidine moiety.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(4-Methyl-2-Pyrimidinyl)-4-Piperidinecarboxylic Acid Ethyl Ester
CAS No.	1273680-69-5
Molecular Formula	C13H19N3O2
Molecular Weight	249.31 g/mol
Synonyms	Ethyl 1-(4-methylpyrimidin-2-yl)piperidine-4-carboxylate; 4-Piperidinecarboxylic acid, 1-(4-methyl-2-pyrimidinyl)-, ethyl ester; 1-(4-Methyl-pyrimidin-2-yl)-piperidine-4-carboxylic acid ethyl ester; Ethyl 1-(4-methyl-2-pyrimidinyl)-4-piperidinecarboxylate; 1-(4-Methyl-2-pyrimidinyl)piperidine-4-carboxylic acid ethyl ester; 1-(4-Methyl-2-pyrimidinyl)-4-piperidinecarboxylic acid ethyl ester; 1-(4-Methyl-2-pyrimidinyl)-4-piperidinecarboxylic acid ethyl ester (CAS 1273680-69-5)
EINECS	Contact for details

Quality Control

Our 1-(4-Methyl-2-Pyrimidinyl)-4-Piperidinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.