Description

n-α-Trityl-o-Benzyl-D-Serine Diethylamine is a sophisticated, non-natural amino acid derivative designed for advanced synthetic applications. This compound is a critical chiral building block, offering high stereochemical purity for the construction of complex peptides and pharmaceutical intermediates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development. The product's protected functional groups provide strategic advantages in multi-step organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected D-serine derivative for the controlled assembly of custom peptide sequences with specific stereochemistry.
• Medicinal Chemistry Research: Serves as a crucial building block in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for candidate drugs during clinical development phases.
• Bioconjugation and Labeling: The reactive handles can be utilized for attaching probes, tags, or other molecules to peptides.
• Academic and Industrial R&D: Fundamental research tool for exploring new synthetic methodologies and developing novel bioactive compounds.

Basic Information

Product Name	n-α-Trityl-o-Benzyl-D-Serine Diethylamine
CAS No.	1272755-21-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	D-Serine, N-(triphenylmethyl)-O-(phenylmethyl)-, compd. with N-ethylethanamine (1:1); Fmoc-D-Ser(Bzl)-OH related protected amino acid; N-α-Trityl-O-benzyl-D-serine diethylamine salt; D-Ser(Bzl)-OH(Trt) diethylamine; Protected D-Serine derivative; Trt-D-Ser(Bzl)-OH·Et2NH; Chiral serine building block; Amino acid protecting group reagent.
EINECS	Contact for details

Quality Control

Our n-α-Trityl-o-Benzyl-D-Serine Diethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.