Description

Bzl,Me-L-Met-Ome Hcl is a protected amino acid derivative, specifically an O-methyl ester of N-benzyloxycarbonyl-L-methionine. This compound is a crucial building block in peptide synthesis, offering selective protection for the carboxylic acid group while the amine is blocked, enabling controlled chain elongation. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of methionine residues into peptide sequences.
• Solution-Phase Peptide Chemistry: Used in classical coupling strategies for constructing complex peptides and natural products.
• Pharmaceutical Research: Serves as a precursor in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific modification of proteins or other biomolecules.
• Chemical Biology: Employed in the synthesis of labeled peptides for metabolic studies and probe development.
• Academic Research: A standard reagent in university and institutional labs for teaching and advancing synthetic methodology.

Basic Information

Product Name	Bzl,Me-L-Met-Ome Hcl
CAS No.	1272754-99-0
Molecular Formula	C15H22ClNO4S
Molecular Weight	347.86 g/mol
Synonyms	N-Cbz-L-Methionine Methyl Ester Hydrochloride; Z-L-Met-OMe·HCl; Nα-Carbobenzoxy-L-methionine methyl ester hydrochloride; (S)-Methyl 2-(((benzyloxy)carbonyl)amino)-4-(methylthio)butanoate hydrochloride; Cbz-Met-OMe HCl; Benzyloxycarbonyl-L-methionine methyl ester hydrochloride; N-Benzyloxycarbonyl-L-methionine methyl ester hydrochloride; Z-Met-OMe·HCl
EINECS	Contact for details

Quality Control

Our Bzl,Me-L-Met-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.