Description

Fmoc-D-Orn(Ivdde)-Oh CAS NO 1272754-86-5 is a specialized, orthogonally protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for constructing complex peptides with high precision, offering superior control over side-chain reactivity during multi-step synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptide-based diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of peptides, particularly those requiring complex architectures.
• Pharmaceutical Research & Development: Used in the synthesis of peptide drug candidates, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation and Labeling: The orthogonal protecting groups (Fmoc and Ivdde) enable selective deprotection for site-specific conjugation with fluorescent dyes, biotin, or other functional molecules.
• Combinatorial Chemistry Libraries: Serves as a valuable component in generating diverse peptide libraries for high-throughput screening against biological targets.
• Academic Research: Employed in biochemistry and chemical biology laboratories for studying protein-protein interactions, signal transduction, and developing novel research probes.

Basic Information

Product Name	Fmoc-D-Orn(Ivdde)-Oh
CAS No.	1272754-86-5
Molecular Formula	C₃₀H₃₇N₃O₇
Molecular Weight	551.63 g/mol
Synonyms	Fmoc-D-ornithine(ivDde)-OH; N-α-Fmoc-N-δ-(ivDde)-D-ornithine; (2R)-5-[[(4S)-4,6-Dimethyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid; Fmoc-D-Orn(ivDde)-OH; N-δ-(1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl)-N-α-(9-fluorenylmethoxycarbonyl)-D-ornithine; Fmoc-D-Orn(ivDde); Fmoc-D-Ornithine(ivDde)-OH
EINECS	Contact for details

Quality Control

Every batch of Fmoc-D-Orn(Ivdde)-Oh undergoes rigorous analytical testing to ensure identity, purity, and consistency suitable for sensitive research and development applications. Our quality assurance protocols include HPLC for purity determination, MS and NMR for structural confirmation, and chiral analysis to verify enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.