Description

4-Bromo-1-(2,2-Diethoxyethoxy)-2-Fluorobenzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and ether-functionalized aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for scale-up and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in the development of fluorinated and brominated aromatic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the fluorine and bromine substituents impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and material science applications.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex molecular architectures via cross-coupling and functional group transformations.
• Fluorine Chemistry: Essential for introducing fluorine atoms into target molecules, a common strategy in modern drug design to improve metabolic stability and bioavailability.

Basic Information

Product Name	4-Bromo-1-(2,2-Diethoxyethoxy)-2-Fluorobenzene
CAS No.	1271673-78-9
Molecular Formula	C₁₂H₁₆BrFO₃
Molecular Weight	307.16 g/mol
Synonyms	2-Bromo-5-(2,2-diethoxyethoxy)fluorobenzene; 1-Bromo-4-(2,2-diethoxyethoxy)-2-fluorobenzene; 4-Bromo-2-fluoro-1-(2,2-diethoxyethoxy)benzene; 2-Fluoro-5-bromophenoxyacetaldehyde diethyl acetal; Benzene, 4-bromo-1-(2,2-diethoxyethoxy)-2-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(2,2-Diethoxyethoxy)-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.