Description

1-[3-Nitro-5-(Trifluoromethyl)Phenyl]Ethylamine is a high-purity, specialized aromatic amine building block featuring both nitro and trifluoromethyl substituents. This compound is critical for advanced research and development, offering a unique combination of electronic and steric properties for creating novel molecular architectures. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, dyes, and liquid crystals.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and other transformations to introduce complex aromatic amine functionalities.
• Life Science Research: Utilized as a biochemical probe or a scaffold for developing enzyme inhibitors and receptor ligands in academic and industrial research laboratories.

Basic Information

Item	Details
Product Name	1-[3-Nitro-5-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	1270542-79-4
Molecular Formula	C9H9F3N2O2
Molecular Weight	234.18 g/mol
Synonyms	1-(3-Nitro-5-(trifluoromethyl)phenyl)ethan-1-amine; α-Methyl-3-nitro-5-(trifluoromethyl)benzylamine; 1-(3-Nitro-5-(trifluoromethyl)phenyl)ethylamine; 3-Nitro-5-(trifluoromethyl)phenethylamine derivative; 2-(3-Nitro-5-(trifluoromethyl)phenyl)propan-2-amine (related isomer); (RS)-1-[3-Nitro-5-(trifluoromethyl)phenyl]ethylamine
EINECS	Contact for details

Quality Control

Our production of 1-[3-Nitro-5-(Trifluoromethyl)Phenyl]Ethylamine adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from oxidizing agents and strong bases. Due to its sensitivity, allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Assay	≥ 96.0% (by titration)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.