Description

1-(3-Chloro-2-Fluorophenyl)Ethan-1-Amine is a versatile fluorinated and chlorinated aromatic amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring both halogen substituents on the phenyl ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery programs.
• Agrochemical Synthesis: Serves as a crucial building block in the synthesis of advanced herbicides, fungicides, and insecticides, where the halogenated aromatic core contributes to biological activity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs), leveraging its amine functionality and halogenated aromatic system.
• Material Science Research: Employed as a monomer or functionalization agent in the synthesis of specialty polymers, dyes, and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and fluorescent tags for biochemical and diagnostic research applications.

Basic Information

Product Name	1-(3-Chloro-2-Fluorophenyl)Ethan-1-Amine
CAS No.	1270509-22-2
Molecular Formula	C8H9ClFN
Molecular Weight	173.61 g/mol
Synonyms	1-(3-Chloro-2-fluorophenyl)ethanamine; α-Methyl-3-chloro-2-fluoroaniline; 1-Aminoethyl-3-chloro-2-fluorobenzene; (3-Chloro-2-fluorophenyl)ethanamine; 1-(3-Chloro-2-fluorophenyl)ethylamine; 2-Fluoro-3-chloro-α-methylbenzylamine; 1-(3-Chloro-2-fluorophenyl)ethan-1-amine (IUPAC); 3-Chloro-2-fluoro-α-methylbenzylamine
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-2-Fluorophenyl)Ethan-1-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.