Description

2-Amino-2-(3-Fluoro-2-Methylphenyl)Ethan-1-Ol is a specialized chiral amino alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino and a hydroxyl group on a chiral center adjacent to a fluorinated aromatic ring, makes it a valuable precursor for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Ligand Synthesis: Used for the preparation of chiral ligands and catalysts for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block in the development of new, high-efficacy pesticides and herbicides with optimized stereochemistry.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced functional materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	2-Amino-2-(3-Fluoro-2-Methylphenyl)Ethan-1-Ol
CAS No.	1270477-85-4
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	2-Amino-2-(3-fluoro-2-methylphenyl)ethanol; 1-(3-Fluoro-2-methylphenyl)-2-aminoethanol; (R/S)-2-Amino-2-(3-fluoro-2-methylphenyl)ethan-1-ol; 2-(3-Fluoro-2-methylphenyl)-2-aminoethanol; α-Amino-3-fluoro-2-methylbenzenemethanol; 3-Fluoro-2-methyl-β-amino-phenethyl alcohol; Amino alcohol intermediate 1270477-85-4
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(3-Fluoro-2-Methylphenyl)Ethan-1-Ol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity and chiral assay, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.