Description

1-(2-Fluoro-3-Methoxyphenyl)Ethan-1-Amine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring both fluorine and methoxy substituents, enables precise modulation of electronic and steric properties in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly as a key intermediate in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of advanced polymers and specialty materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or affinity probes for studying biological systems and target engagement.
• Academic and Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1-(2-Fluoro-3-Methoxyphenyl)Ethan-1-Amine
CAS No.	1270461-41-0
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	1-(2-Fluoro-3-methoxyphenyl)ethanamine; α-Methyl-2-fluoro-3-methoxybenzylamine; 1-(2-Fluoro-3-methoxyphenyl)ethylamine; 2-Fluoro-3-methoxy-α-methylbenzylamine; (1-(2-Fluoro-3-methoxyphenyl)ethyl)amine; 2-Fluoro-3-methoxyamphetamine (structural analog); 2-F-3-MeO-PEA (abbrev.); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-3-Methoxyphenyl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.