Description

1-(3-Fluoro-5-Methylphenyl)Ethan-1-Amine is a high-purity fluorinated aromatic amine building block of significant synthetic utility. This compound is valued for its role as a key intermediate in the development of advanced pharmaceutical and agrochemical agents, where its unique fluorine-substituted aromatic core imparts desirable biological and physicochemical properties. It is primarily sought by R&D chemists and process development scientists in the life sciences and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	1-(3-Fluoro-5-Methylphenyl)Ethan-1-Amine
CAS No.	1270461-30-7
Molecular Formula	C9H12FN
Molecular Weight	153.20 g/mol
Synonyms	1-(3-Fluoro-5-methylphenyl)ethanamine; α-Methyl-3-fluoro-5-methylbenzylamine; 1-(3-Fluoro-5-methylphenyl)ethylamine; 3-Fluoro-5-methyl-α-methylbenzylamine; 1-(3-Fluoro-5-methylphenyl)ethan-1-amine; (RS)-1-(3-Fluoro-5-methylphenyl)ethanamine; 3-Fluoro-5-methylphenethylamine derivative
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-5-Methylphenyl)Ethan-1-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our quality systems support development under ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.