Description

1-(2-Fluoro-5-Methylphenyl)Ethan-1-Amine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular structure, which incorporates both fluorine and an amine functional group on a substituted phenyl ring, enabling precise modifications to the physicochemical properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Research: Serves as a critical building block for developing new generation herbicides, fungicides, and insecticides, leveraging the fluorine substituent to improve lipophilicity and target binding.
• Ligand Synthesis for Catalysis: Used in the preparation of specialized ligands for transition metal catalysts, which are employed in asymmetric synthesis and cross-coupling reactions.
• Material Science Precursor: Employed in the research and development of advanced polymers and functional materials, where the aromatic amine can be incorporated into monomer designs.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes to study biological processes and enzyme mechanisms.

Basic Information

Product Name	1-(2-Fluoro-5-Methylphenyl)Ethan-1-Amine
CAS No.	1270440-32-8
Molecular Formula	C9H12FN
Molecular Weight	153.20 g/mol
Synonyms	1-(2-Fluoro-5-methylphenyl)ethanamine; α-Methyl-2-fluoro-5-methylbenzylamine; 1-(2-Fluoro-5-methylphenyl)ethylamine; 2-Fluoro-5-methyl-α-methylbenzylamine; 1-(2-Fluoro-5-tolyl)ethan-1-amine; 2-Fluoro-5-methylphenethylamine (related); (RS)-1-(2-Fluoro-5-methylphenyl)ethanamine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-5-Methylphenyl)Ethan-1-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent quality suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.