Description

1-(2-Chloro-5-Fluorophenyl)Ethylamine is a high-purity, halogenated aromatic amine building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents, makes it a critical intermediate for creating molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the halogenated phenyl group enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(2-Chloro-5-Fluorophenyl)Ethylamine
CAS No.	1270439-83-2
Molecular Formula	C8H9ClFN
Molecular Weight	173.61 g/mol
Synonyms	α-Methyl-2-chloro-5-fluoro-benzeneethanamine; (1-(2-Chloro-5-fluorophenyl)ethyl)amine; 2-Chloro-5-fluoro-α-methylbenzeneethanamine; 1-(2-Chloro-5-fluorophenyl)ethan-1-amine; (R/S)-1-(2-Chloro-5-fluorophenyl)ethylamine; 2-Chloro-5-fluoro-α-methylphenethylamine; Benzenemethanamine, 2-chloro-5-fluoro-α-methyl-
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-5-Fluorophenyl)Ethylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality, it should be stored separately from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	Contact for details (Racemic or Enantiopure grades available)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.