Description

n-Fmoc-D-Tyrosine Methyl Ester is a protected, non-natural amino acid derivative essential for solid-phase peptide synthesis (SPPS). This high-purity building block is critical for researchers and manufacturers creating complex peptides with precise stereochemistry and functional group control. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc/t-Bu strategy, enabling the controlled assembly of peptide chains.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation & Probe Synthesis: Serves as a precursor for introducing tyrosine-derived phenolic groups into biomolecules for labeling or cross-linking.
• Combinatorial Chemistry: A valuable component in libraries for screening bioactive compounds and structure-activity relationship (SAR) studies.
• Academic & Institutional Research: Employed in biochemical studies investigating protein-protein interactions and enzyme mechanisms.

Basic Information

Product Name	n-Fmoc-D-Tyrosine Methyl Ester
CAS No.	1270300-64-5
Molecular Formula	C26H25NO6
Molecular Weight	447.48 g/mol
Synonyms	Fmoc-D-Tyr-OMe; Fmoc-D-Tyrosine Methyl Ester; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid methyl ester; D-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester; Methyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propanoate; N-α-Fmoc-D-tyrosine methyl ester; FMOC-D-TYR-OME
EINECS	Contact for details

Quality Control

Our n-Fmoc-D-Tyrosine Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards to support our customers' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.