Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2,3-Dimethylphe is a specialized amino acid derivative belonging to the Fmoc-protected class, designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity, stereochemically defined building blocks to ensure the integrity and biological activity of complex peptides. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and fine chemical suppliers engaged in the development of therapeutic peptides, peptidomimetics, and novel drug candidates.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid, it serves as a key monomer for the sequential assembly of custom peptide sequences.
• Pharmaceutical Intermediate: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Design: Incorporates the unique D-2,3-dimethylphenylalanine side chain to create peptides with enhanced metabolic stability, receptor selectivity, and bioavailability.
• Bioconjugation and Labeling: Acts as a precursor for introducing specific aromatic, hydrophobic moieties into peptides for structural studies or functionalization.
• Academic and Industrial Research: Essential for biochemical studies exploring protein-protein interactions, enzyme substrates, and novel bioactive peptides.
• Custom Peptide Service Providers: A critical raw material for CROs and CMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2,3-Dimethylphe
CAS No.	1270290-64-6
Molecular Formula	C27H27NO4
Molecular Weight	429.51 g/mol
Synonyms	Fmoc-D-2,3-dimethylphenylalanine; Fmoc-D-2,3-Dimethylphe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-2,3-dimethylphenylalanine; Fmoc-D-2,3-diMePhe; N-Fmoc-3-(2,3-dimethylphenyl)-D-alanine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dimethylphenyl)propanoic acid; Fmoc-D-2,3-Dmp-OH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2,3-Dimethylphe is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive applications like peptide synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.