Description

α-Me-Phe(4-Ocf 3 )-Oh CAS NO 1269926-90-0 is a non-natural, fluorinated phenylalanine derivative, specifically an α-methyl-4-(trifluoromethoxy)phenylalanine. This compound is a highly valuable building block in advanced organic synthesis, prized for introducing steric hindrance and lipophilicity into target molecules. It is primarily utilized by pharmaceutical research and development teams for the synthesis of novel peptide-based therapeutics and bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel peptide drugs and protease inhibitors.
• Peptidomimetics Research: Used to create modified peptides with enhanced metabolic stability and binding affinity.
• Medicinal Chemistry: Incorporation into drug candidates to modulate physicochemical properties like lipophilicity and bioavailability.
• Chemical Biology Probes: Synthesis of labeled or tagged peptides for studying biological pathways and protein interactions.
• Agrochemical Research: Potential intermediate in the development of advanced, bioactive compounds.
• Academic & Contract Research: Serves as a specialized reagent for synthetic chemistry projects in university and CRO laboratories.

Basic Information

Product Name	α-Me-Phe(4-Ocf 3 )-Oh
CAS No.	1269926-90-0
Molecular Formula	C11H12F3NO3
Molecular Weight	263.21 g/mol
Synonyms	α-Methyl-4-(trifluoromethoxy)-L-phenylalanine; (S)-2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid, α-methyl derivative; 2-Amino-2-methyl-3-[4-(trifluoromethoxy)phenyl]propanoic acid; Fmoc-α-Me-Phe(4-OCF3)-OH (protected form); Boc-α-Me-Phe(4-OCF3)-OH (protected form); Non-natural fluorinated amino acid; 4-(Trifluoromethoxy)-α-methylphenylalanine
EINECS	Contact for details

Quality Control

Our α-Me-Phe(4-Ocf 3 )-Oh is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical specifications to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.