Description

Carbamic Acid, n-[(1S)-2-[[4-[3-(3-Amino-5-Chloro-2-Fluorophenyl)-1-(1-Methylethyl)-1H-Pyrazol-4-Yl]-2-Pyrimidinyl]Amino]-1-Methylethyl]-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly within oncology and other specialized treatment areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Oncology Drug Research: Used in the research and development of targeted cancer therapies due to its specific molecular scaffold.
• Kinase Inhibitor Synthesis: A key structural component in the creation of potential kinase inhibitor candidates for various disease pathways.
• Preclinical & Clinical Development: Supplied to support drug discovery programs from lead optimization through to clinical trial material (CTM) production.
• Contract Manufacturing (CMO): Provided to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.

Basic Information

Item	Details
Product Name	Carbamic Acid, n-[(1S)-2-[[4-[3-(3-Amino-5-Chloro-2-Fluorophenyl)-1-(1-Methylethyl)-1H-Pyrazol-4-Yl]-2-Pyrimidinyl]Amino]-1-Methylethyl]-, Methyl Ester
CAS No.	1269440-78-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(S)-Methyl (1-(4-(3-(3-amino-5-chloro-2-fluorophenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-yl)carbamate; UNII-7J2S5I8K1G; 7J2S5I8K1G; Methyl (1S)-2-[[4-[3-(3-amino-5-chloro-2-fluorophenyl)-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-1-methylethylcarbamate; Carbamic acid, N-[(1S)-2-[[4-[3-(3-amino-5-chloro-2-fluorophenyl)-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-1-methylethyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[(1S)-2-[[4-[3-(3-Amino-5-Chloro-2-Fluorophenyl)-1-(1-Methylethyl)-1H-Pyrazol-4-Yl]-2-Pyrimidinyl]Amino]-1-Methylethyl]-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.