Description

5-Bromo-1-(Pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile is a high-value, heterocyclic organic building block designed for advanced chemical synthesis. This compound matters because it serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential building block for advanced organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	5-Bromo-1-(Pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile
CAS No.	1269291-98-6
Molecular Formula	C8H4BrN5
Molecular Weight	250.06 g/mol
Synonyms	5-Bromo-1-(2-pyrimidinyl)-1H-pyrazole-4-carbonitrile; 1H-Pyrazole-4-carbonitrile, 5-bromo-1-(2-pyrimidinyl)-; 1269291-98-6; 5-Bromo-1-pyrimidin-2-yl-1H-pyrazole-4-carbonitrile; 5-Bromo-1-(2-pyrimidyl)-1H-pyrazole-4-carbonitrile; 5-Bromo-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile; 5-Bromo-1-(2-pyrimidinyl)-1H-pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(Pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.