Description

4-(Pyridin-3-Yl)-2-(Trifluoromethyl)Pyrimidine is a high-value heterocyclic building block characterized by its pyridine and trifluoromethyl-substituted pyrimidine core. This compound is essential for medicinal chemistry research and development, offering a versatile scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of advanced drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Agrochemical Development: Serves as a precursor in the research of advanced pesticides and herbicides.
• Material Science: Investigated as a component for organic electronic materials and liquid crystals.
• Chemical Biology: Employed in the development of molecular probes and enzyme inhibitors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4-(Pyridin-3-Yl)-2-(Trifluoromethyl)Pyrimidine
CAS No.	1269291-91-9
Molecular Formula	C10H6F3N3
Molecular Weight	225.17 g/mol
Synonyms	2-(Trifluoromethyl)-4-(3-pyridinyl)pyrimidine; 4-(3-Pyridinyl)-2-(trifluoromethyl)pyrimidine; 4-Pyridin-3-yl-2-trifluoromethylpyrimidine; 3-(2-Trifluoromethylpyrimidin-4-yl)pyridine; Pyrimidine, 4-(3-pyridinyl)-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-(Pyridin-3-Yl)-2-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.