Description

(4-Bromo-Pyrimidin-2-Yl)-Cyclopentyl-Amine is a high-purity brominated pyrimidine derivative, a crucial building block in modern organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds and molecular probes for studying biological mechanisms.
• Material Science: Employed in the research and development of organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Acts as a valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to introduce the pyrimidine scaffold.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial catalog items.

Basic Information

Product Name	(4-Bromo-Pyrimidin-2-Yl)-Cyclopentyl-Amine
CAS No.	1269291-43-1
Molecular Formula	C9H12BrN3
Molecular Weight	242.12 g/mol
Synonyms	N-Cyclopentyl-4-bromopyrimidin-2-amine; 4-Bromo-N-cyclopentylpyrimidin-2-amine; 2-Amino-4-bromopyrimidine cyclopentyl derivative; Cyclopentyl-(4-bromopyrimidin-2-yl)amine; 4-Bromo-2-(cyclopentylamino)pyrimidine; (4-Bromo-2-pyrimidinyl)cyclopentylamine; 1269291-43-1
EINECS	Contact for details

Quality Control

Our (4-Bromo-Pyrimidin-2-Yl)-Cyclopentyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP (current Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.