Description

2-(1-(2-Nitrophenyl)-1H-Pyrazol-5-Yl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its precise chemical framework to create targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides, where its heterocyclic core can contribute to biological activity.
• Material Science: Investigated as a monomer or building block for creating specialized polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Dye & Pigment Synthesis: Acts as an intermediate for developing novel colorants and functional dyes due to its conjugated aromatic system.

Basic Information

Item	Details
Product Name	2-(1-(2-Nitrophenyl)-1H-Pyrazol-5-Yl)Pyrimidine
CAS No.	1269291-40-8
Molecular Formula	C₁₃H₉N₅O₂
Molecular Weight	267.25 g/mol
Synonyms	2-[1-(2-Nitrophenyl)-1H-pyrazol-5-yl]pyrimidine; 2-(1-(2-Nitrophenyl)-1H-pyrazol-5-yl)pyrimidine; Pyrimidine, 2-[1-(2-nitrophenyl)-1H-pyrazol-5-yl]-; 1269291-40-8; 2-(1-(2-Nitrophenyl)-1H-pyrazol-5-yl)pyrimidine; 2-(1-(2-Nitro-phenyl)-1H-pyrazol-5-yl)-pyrimidine
EINECS	Contact for details

Quality Control

Our 2-(1-(2-Nitrophenyl)-1H-Pyrazol-5-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.