Description

3-Bromo-2,5-Difluoroaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role in introducing both bromine and fluorine substituents onto an aromatic amine scaffold, enabling precise modulation of electronic and steric properties in target molecules. It is primarily needed by pharmaceutical, agrochemical, and specialty chemical R&D teams for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, where the difluoro and bromo groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in organic light-emitting diodes (OLEDs) and liquid crystal displays (LCDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart flame retardancy, thermal stability, and specific optical properties.
• Dye & Pigment Intermediate: Used in the synthesis of complex, high-performance dyes and pigments for imaging and coating applications.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl and heteroaryl structures.

Basic Information

Product Name	3-Bromo-2,5-Difluoroaniline
CAS No.	1269232-99-6
Molecular Formula	C6H4BrF2N
Molecular Weight	208.00 g/mol
Synonyms	2,5-Difluoro-3-bromoaniline; 3-Bromo-2,5-difluorobenzenamine; Benzenamine, 3-bromo-2,5-difluoro-; 3-Br-2,5-F2-C6H2NH2; 2-Amino-4-bromo-1,5-difluorobenzene; 3-Bromo-2,5-difluoro-phenylamine; (3-Bromo-2,5-difluorophenyl)amine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,5-Difluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.