Description

Butanoic Acid, 4-[[3-(4-Chlorobenzoyl)-4,5-Dimethyl-2-Thienyl]Amino]-3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Oxo-, 1,1-Dimethylethyl Ester, (3S)- is a sophisticated, high-purity pharmaceutical intermediate designed for advanced synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the construction of complex molecules with specific stereochemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Peptidomimetic Synthesis: The protected amino acid derivative structure makes it valuable for constructing peptide-like molecules with enhanced stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material or intermediate for CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Protease Inhibitor Development: Its structural features are relevant for the research and development of enzyme inhibitors.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	Butanoic Acid, 4-[[3-(4-Chlorobenzoyl)-4,5-Dimethyl-2-Thienyl]Amino]-3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Oxo-, 1,1-Dimethylethyl Ester, (3S)-
CAS No.	1268524-65-7
Molecular Formula	C37H35ClN2O6S
Molecular Weight	671.20 g/mol
Synonyms	(3S)-4-[[3-(4-Chlorobenzoyl)-4,5-dimethyl-2-thienyl]amino]-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-oxobutanoic acid 1,1-dimethylethyl ester; tert-Butyl (3S)-4-({3-[(4-chlorophenyl)carbonyl]-4,5-dimethyl-2-thienyl}amino)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-oxobutanoate; Fmoc-D-2-Thienylalanine(Pbf) tert-Butyl Ester derivative; Advanced Pharmaceutical Intermediate 1268524-65-7; Nα-Fmoc-Nβ-[3-(4-chlorobenzoyl)-4,5-dimethyl-2-thienyl]-D-asparagine tert-butyl ester; Custom Synthetic Building Block 1268524-65-7
EINECS	Contact for details

Quality Control

Our Butanoic Acid derivative is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and development applications. All batches undergo comprehensive analytical characterization, including HPLC for purity assessment, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.