Description

(1S)-1-(Pyrimidin-2-Yl)Ethan-1-Amine is a high-purity chiral amine building block of significant importance in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical synthesis, and advanced material science who require enantiomerically pure intermediates for their processes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and protein function.
• Advanced Material Research: Investigated as a building block for functionalized polymers and organic electronic materials with specific chiral properties.

Basic Information

Product Name	(1S)-1-(Pyrimidin-2-Yl)Ethan-1-Amine
CAS No.	1268492-93-8
Molecular Formula	C6H9N3
Molecular Weight	123.16 g/mol
Synonyms	(S)-1-(Pyrimidin-2-yl)ethan-1-amine; (S)-1-(2-Pyrimidinyl)ethylamine; (1S)-1-(2-Pyrimidinyl)ethylamine; (S)-(-)-1-(2-Pyrimidinyl)ethylamine; (S)-α-Methyl-2-pyrimidinemethanamine; (S)-2-(1-Aminoethyl)pyrimidine; (S)-1-Aminoethylpyrimidine
EINECS	Contact for details

Quality Control

Our (1S)-1-(Pyrimidin-2-Yl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.