Description

2-Amino-n-[3-[[2-(4-Methyl-1-Piperazinyl)-4-(Phenylmethoxy)-5-Pyrimidinyl]Thio]Phenyl] is a high-purity, complex heterocyclic compound designed for advanced research and pharmaceutical development. This molecule is of significant interest as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) building block due to its intricate structure featuring pyrimidine, piperazine, and thioether functionalities. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) research.
• Kinase Inhibitor Research: Used in the development and screening of novel kinase inhibitors, leveraging its pyrimidine core which is a common pharmacophore in this drug class.
• Chemical Biology Probe: Employed as a tool compound to study specific biological pathways and protein interactions in academic and industrial research settings.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production under current Good Manufacturing Practice (cGMP) guidelines for clinical trial material.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Custom Synthesis Building Block: Available for contract research organizations (CROs) and companies requiring bespoke molecular entities for proprietary discovery programs.

Basic Information

Item	Details
Product Name	2-Amino-n-[3-[[2-(4-Methyl-1-Piperazinyl)-4-(Phenylmethoxy)-5-Pyrimidinyl]Thio]Phenyl]
CAS No.	1268273-90-0
Molecular Formula	C22H24N6OS
Molecular Weight	412.53 g/mol
Synonyms	2-Amino-N-(3-((2-(4-methylpiperazin-1-yl)-4-(benzyloxy)pyrimidin-5-yl)thio)phenyl)acetamide (common IUPAC variant); UNII-7Q8K3F5B2S; 7Q8K3F5B2S; 2-Acetamido-N-[3-[[2-(4-methyl-1-piperazinyl)-4-(phenylmethoxy)-5-pyrimidinyl]thio]phenyl] (related amide); Potential proprietary/research codes based on parent structure.
EINECS	Contact for details

Quality Control

Our 2-Amino-n-[3-[[2-(4-Methyl-1-Piperazinyl)-4-(Phenylmethoxy)-5-Pyrimidinyl]Thio]Phenyl] is produced and controlled under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting specifications for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (argon or nitrogen) in a sealed container. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.