Description

L(+)-Isovaline Monohydrate is a high-purity, non-proteinogenic amino acid derivative, recognized for its unique structural and stereochemical properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the study of chiral pharmacology and as a potential building block for novel therapeutics. It serves as a critical chiral intermediate and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Biochemical Research: Used as a reference standard and reagent in studies of amino acid transport, metabolism, and chiral recognition processes.
• Peptide Synthesis: Incorporation into custom peptides to study structure-activity relationships and to create peptides with enhanced stability or novel biological functions.
• Neuroscience Research: Investigation of its potential neuromodulatory effects and interactions with neurotransmitter systems, given its structural similarity to other neuroactive amino acids.
• Analytical Standard: Serves as a high-purity calibration standard for analytical methods such as HPLC, LC-MS, and chiral chromatography in quality control laboratories.
• Fine Chemical Synthesis: Utilized in asymmetric synthesis and as a precursor for more complex chiral molecules in advanced organic chemistry.

Basic Information

Product Name	L(+)-Isovaline Monohydrate
CAS No.	1266371-20-3
Molecular Formula	C5H11NO3 • H2O
Molecular Weight	151.15 g/mol (Anhydrous basis: 133.15)
Synonyms	(S)-2-Amino-2-methylbutanoic acid monohydrate; L-2-Amino-2-methylbutyric acid hydrate; (S)-2-Amino-2-methylbutyric acid monohydrate; L-Isovaline hydrate; (S)-Isovaline monohydrate; 2-Amino-2-methylbutanoic acid, L-, monohydrate; α-Aminoisovaleric acid, L-, monohydrate
EINECS	Contact for details

Quality Control

Our L(+)-Isovaline Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA), which include data from chiral HPLC, NMR, and elemental analysis. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	10.0% - 13.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.