Description

4-(4,4-Difluoro-1-Piperidyl)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a difluorinated piperidine core linked to an aniline moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutics.
• Agrochemical Development: Serves as a precursor in the creation of novel pesticides and herbicides.
• Ligand Synthesis: Useful for constructing complex ligands in catalysis and material science.
• Fluorinated Compound Libraries: An essential component for generating diverse screening libraries in drug discovery.

Basic Information

Product Name	4-(4,4-Difluoro-1-Piperidyl)Aniline
CAS No.	1266330-18-0
Molecular Formula	C11H14F2N2
Molecular Weight	212.24 g/mol
Synonyms	4-(4,4-Difluoropiperidin-1-yl)aniline; 1-(4-Aminophenyl)-4,4-difluoropiperidine; 4-Aminophenyl-4,4-difluoropiperidine; 4,4-Difluoro-1-(4-aminophenyl)piperidine; 4-(4,4-Difluoropiperidino)aniline; 4-(4,4-Difluoro-1-piperidinyl)benzenamine; Aniline, 4-(4,4-difluoro-1-piperidinyl)-
EINECS	Contact for details

Quality Control

Our 4-(4,4-Difluoro-1-Piperidyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.