Description

2-Chloro-3-Fluoro-6-Hydroxybenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique substitution pattern, featuring chloro, fluoro, and hydroxy groups ortho to the formyl group, makes it a critical precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Serves as a core building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Acts as a starting point for synthesizing fluorescent tags or molecular probes for biochemical assays.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	2-Chloro-3-Fluoro-6-Hydroxybenzaldehyde
CAS No.	1263378-00-2
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	3-Fluoro-2-chloro-6-hydroxybenzaldehyde; 6-Hydroxy-2-chloro-3-fluorobenzaldehyde; 2-Chloro-3-fluoro-6-hydroxy-benzaldehyde; Benzaldehyde, 2-chloro-3-fluoro-6-hydroxy-; 1263378-00-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Fluoro-6-Hydroxybenzaldehyde is produced under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. Our standard quality control includes identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A Certificate of Analysis (COA) detailing batch-specific results is available for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.