Description

2-(2-Amino-5-Bromo-6-Hydroxy-Pyrimidin-4-Yl)-Benzoic Acid is a high-purity, functionalized heterocyclic building block that serves as a critical intermediate in advanced organic synthesis. Its unique molecular architecture, featuring both a pyrimidine and a benzoic acid moiety, makes it an invaluable precursor for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in antiviral, anticancer, and CNS-active therapeutic areas.
• Agrochemical Synthesis: Used as a building block in the creation of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand & Catalyst Development: Potential use in the synthesis of specialized ligands for metal catalysis or molecular recognition applications.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials or functional polymers.

Basic Information

Product Name	2-(2-Amino-5-Bromo-6-Hydroxy-Pyrimidin-4-Yl)-Benzoic Acid
CAS No.	1263283-37-9
Molecular Formula	C11H8BrN3O3
Molecular Weight	310.11 g/mol
Synonyms	2-(2-Amino-5-bromo-6-hydroxypyrimidin-4-yl)benzoic acid; 4-(2-Carboxyphenyl)-5-bromo-2,6-dihydroxypyrimidine; 5-Bromo-2,6-dihydroxy-4-(2-carboxyphenyl)pyrimidine; Benzoic acid, 2-(2-amino-5-bromo-6-hydroxy-4-pyrimidinyl)-; 2-Amino-5-bromo-6-hydroxy-4-(2-carboxyphenyl)pyrimidine; 4-(2-Carboxyphenyl)-5-bromo-6-hydroxy-2-aminopyrimidine
EINECS	Contact for details

Quality Control

Our production of 2-(2-Amino-5-Bromo-6-Hydroxy-Pyrimidin-4-Yl)-Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting R&D and cGMP-grade standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for purity, residual solvents, and heavy metals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.