Description

5-Chloro-3-Iodo-2-Methylpyrazolo[1,5-A]Pyrimidine is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the discovery and development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated pyrazolopyrimidine structure for bioactivity.
• Material Science Precursor: Serves as a specialized monomer or precursor in the creation of organic electronic materials and advanced polymers.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.
• Academic & Institutional Research: Essential for universities and research institutes conducting fundamental studies in heterocyclic chemistry and reaction methodology.

Basic Information

Product Name	5-Chloro-3-Iodo-2-Methylpyrazolo[1,5-A]Pyrimidine
CAS No.	1263282-98-9
Molecular Formula	C7H5ClIN3
Molecular Weight	309.49 g/mol
Synonyms	2-Methyl-5-chloro-3-iodopyrazolo[1,5-a]pyrimidine; 5-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 5-chloro-3-iodo-2-methyl-; 5-Chloro-3-iodo-2-methyl-1H-pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Iodo-2-Methylpyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.