Description

4-Cyclopropyl-2-(Methylthio)-6-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional heterocyclic building block characterized by its cyclopropyl and trifluoromethyl substituents. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical R&D teams for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group often enhances lipophilicity and bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and other functional materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging agent in probe development for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Cyclopropyl-2-(Methylthio)-6-(Trifluoromethyl)Pyrimidine
CAS No.	1263282-49-0
Molecular Formula	C9H9F3N2S
Molecular Weight	234.24 g/mol
Synonyms	2-(Methylthio)-4-cyclopropyl-6-(trifluoromethyl)pyrimidine; 4-Cyclopropyl-2-methylsulfanyl-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4-cyclopropyl-2-(methylthio)pyrimidine; 4-Cyclopropyl-2-(methylmercapto)-6-(trifluoromethyl)pyrimidine; 2-Methylsulfanyl-4-cyclopropyl-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Cyclopropyl-2-(Methylthio)-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.