Description

5-Chloro-2-Fluoro-4-Methyl-Phenylamine is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring strategically placed chloro, fluoro, and methyl substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An important substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for C-N and C-C bond formation.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methyl-Phenylamine
CAS No.	1263275-21-3
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	2-Fluoro-5-chloro-4-methylaniline; 4-Amino-2-chloro-5-fluorotoluene; 5-Chloro-2-fluoro-p-toluidine; 2-Chloro-5-fluoro-4-methylaniline; 4-Methyl-2-fluoro-5-chloroaniline; 5-Chloro-2-fluoro-4-methylbenzenamine; Benzenamine, 5-chloro-2-fluoro-4-methyl-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Methyl-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.