Description

Methyl 6-Bromopyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of potential kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	Methyl 6-Bromopyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	1263060-83-8
Molecular Formula	C8H6BrN3O2
Molecular Weight	256.06 g/mol
Synonyms	6-Bromopyrazolo[1,5-a]pyrimidine-3-carboxylic acid methyl ester; Methyl 6-bromo-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylate; 6-Bromo-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid methyl ester; Methyl 6-bromopyrazolo[1,5-a]pyrimidine-3-carboxylate; 1263060-83-8; Methyl 6-bromo-1,5-dihydropyrazolo[1,5-a]pyrimidine-3-carboxylate; 6-Bromo-3-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromopyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions, preferably with desiccant, to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.