Description

Trt-Dpr(Fmoc)-Oh CAS NO 1263046-25-8 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled and efficient construction of complex peptide sequences for research and therapeutic development. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and CROs engaged in the discovery and production of novel peptide-based drugs and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid for the sequential assembly of custom peptide chains.
• Pharmaceutical Research: Used in the development and scale-up of active pharmaceutical ingredients (APIs) for peptide therapeutics.
• Bioconjugation: Acts as a specialized linker or intermediate for attaching peptides to other molecules, surfaces, or carriers.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive compounds.
• Proteomics and Biochemical Studies: Utilized in the synthesis of substrate analogs, enzyme inhibitors, and labeled peptides for mechanistic studies.
• Antibody-Drug Conjugate (ADC) Development: Serves as a component in constructing specialized peptide linkers for targeted drug delivery systems.

Basic Information

Product Name	Trt-Dpr(Fmoc)-Oh
CAS No.	1263046-25-8
Molecular Formula	C33H30N2O5
Molecular Weight	534.60 g/mol
Synonyms	Fmoc-Dpr(Trt)-OH; Nα-Fmoc-Nω-trityl-L-diaminopropionic acid; Fmoc-L-Dpr(Trt)-OH; N-(9-Fluorenylmethoxycarbonyl)-N'-(trityl)-L-diaminopropionic acid; Fmoc-3-(tritylamino)-L-alanine; (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(tritylamino)propanoic acid; Fmoc-Dap(Trt)-OH; L-2,3-Diaminopropionic acid, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N3-(triphenylmethyl)-
EINECS	Contact for details

Quality Control

Our Trt-Dpr(Fmoc)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.